GBA PD, which refers to genetic Parkinson’s disease with a variant of the glucosidase gene, does not usually present with gastrointestinal symptoms, and may be accompanied by constipation in a few patients. The main symptoms of Parkinson’s disease are categorized into motor and non-motor symptoms. Motor symptoms are mainly manifested as static tremor, and some may be manifested as muscle ankylosis. In the early stage of the disease, patients may experience bradykinesia, inability to complete some fine movements, and postural balance disorders, which may be manifested as forward gait or panicky gait. Parkinson’s disease non-motor symptoms are mainly sensory impairment, especially the sense of smell loss, some will have sleep disorders, such as nighttime dreaming, some patients will have autonomic dysfunction, there may be constipation, excessive sweating, urination disorders. Prolonged onset of the disease can lead to mental disorders, such as anxiety and depression. The main symptoms of Parkinson’s disease are neurological symptoms, and rarely gastrointestinal symptoms, if gastrointestinal symptoms occur, it is considered to be caused by digestive disorders, and should be timely consultation.