Taking vitamin D during puberty will not cause bone closure, which is normally controlled by the body’s hormonal regulation. The main role of vitamin D in the body is to promote gastrointestinal calcium absorption, bone tissue contains a large amount of calcium and collagen, calcium is the raw material for bone tissue growth. However, calcium is not involved in the regulation of bone growth, which is mainly controlled by the body’s thyroxine and growth hormone levels, so that the long bone growth plate grows separately at both ends of the bone. At the end of development, the hormone levels drop, the growth plates stop growing, the bones close, and there is no more growth. Other factors such as fractures, inflammation, tumors, and other undesirable factors may also cause premature closure of the bones, resulting in pathological bone closure.