A wart is actually a verruca, also called common wart, and common warts on the hands are caused by infection of the skin on the hands with the human papilloma virus, with common causes such as low resistance or broken skin. The HPV virus usually infects the skin and parasitizes the skin. When the skin and mucous membranes are broken, the HPV virus infects the basal cells of the epidermis, and the virus replicates, causing proliferation of the squamous epithelium of the skin and mucous membranes, and the emergence of hyperplastic papules, with papillary bumps at the top, which can be accompanied by itching. When the body due to disease or mental stress causes low resistance or skin damage, the human papilloma virus will go through the skin breaks to invade the skin cells, causing the formation of warts. It is recommended to consult with a doctor for targeted treatment under the guidance of the doctor.