Paraquat, a highly toxic pesticide, has an extremely low lethal dose to humans. The drug can cause multiple organ function damage or failure in humans, the most common and prominent of which are often the lungs and kidneys. The most common route of paraquat poisoning in clinical patients is often caused by oral ingestion. Once a human being takes paraquat by mistake or swallows it by suicide, the effective dose ingested by the organism often reaches the lethal dose to the human body. The effect of clinical treatment for paraquat patients depends mainly on the dose of paraquat ingested by the patients and whether the patients are treated with early emetic and early blood purification treatment. For patients with oral ingestion of paraquat poisoning, patients should be treated with emetic, gastric lavage and diarrhea as soon as possible. At the same time, patients should be given some adsorbents such as activated carbon in the stomach to reduce the further absorption of unabsorbed paraquat in the gastrointestinal tract. At the same time, patients can be given rehydration and diuresis to accelerate the excretion of paraquat. If treatment conditions allow, patients should be given blood purification treatment as soon as possible to quickly remove paraquat from the body. To prevent and treat the damage to lungs, kidneys and other organs caused by paraquat, we should take active measures.