Intrahepatic calcified foci may be related to intrahepatic bile duct stones, hepatitis, liver cancer, hepatic schistosomiasis, etc. Patients can be treated by choledochotomy and lithotripsy, use of medication and resection of the lesions. 1. Intrahepatic bile duct stones: Intrahepatic bile duct stones can be treated by choledochotomy and bile-intestinal anastomosis, etc. Symptoms can be effectively improved after treatment, but they may recur, and it is difficult to cure them completely. 2. Hepatitis: intrahepatic calcified foci caused by hepatitis can be treated with drugs such as reduced glutathione, viral hepatitis should be treated with antiviral therapy such as entecavir, etc. Patients also need to take more rests, stop using the drugs that cause liver damage immediately, and strictly abstain from drinking alcohol, and some of the patients can be cured after active treatment. 3. Hepatocellular carcinoma: patients with hepatocellular carcinoma may also have intrahepatic calcified foci, patients can use drugs such as Lenvatinib to inhibit the proliferation of tumor cells, and patients need to undergo hepatic resection at the earliest possible time, which may lead to a certain degree of cure. It is suggested that patients should go to the local hospital as soon as possible to make a clear diagnosis and choose the appropriate treatment plan under the guidance of doctors.