Common causes of overnight vomiting after drinking include damaged gastric mucosa and impaired liver function, etc. Medicines to protect gastric mucosa and liver can be used under the guidance of specialized physicians. 1. Damaged gastric mucosa: If the patient drinks a lot of wine the night before, the alcohol stimulates the gastric mucosa, resulting in damage to the gastric mucosa, and the next day after gastric emptying, the gastric lining cells secrete gastric acid, which exacerbates the stimulation of the gastric mucosa, and this will lead to overnight vomiting. At this time, you need to take drugs to protect the gastric mucosa, such as aluminum hydroxide, bismuth potassium citrate. 2. impaired liver function: the day before drinking a high concentration of white wine, alcohol damage to liver cells can lead to liver function is impaired, the liver’s ability to metabolize alcohol decreased, there is still part of the alcohol stays in the stomach, stimulating the gastric mucosa, can also trigger overnight vomiting. At this time, you can use hepatoprotective drugs for relief, such as diammonium glycyrrhizinate capsules, reduced glutathione and silymarin. If the vomiting symptoms continue to worsen, you need to consult a doctor in time, by a professional doctor for standardized treatment and therapy, do not self-medication, so as not to cause adverse consequences.