Red nose may be due to pityriasis rosea, allergic dermatitis, systemic lupus erythematosus, etc. Interventions can be made with medications such as dexamethasone cream, cetirizine, hormones, and immunosuppressants. 1. pityriasis rosea: medications for pityriasis rosea include topical medications such as glycerite lotion and dexamethasone cream; antihistamines such as loratadine and cetirizine for localized irritation and itching; and acyclovir for viral infections. 2. Allergic dermatitis: its occurrence is related to local allergic reaction, and its topical drugs are the same as that of pityriasis rosea; oral treatment drugs include antihistamines such as loratadine and cetirizine, and glucocorticoid drugs such as dexamethasone. 3. Systemic lupus erythematosus: its therapeutic drugs include acetaminophen, aspirin and other non-steroidal anti-inflammatory drugs, budesonide, dexamethasone and other glucocorticosteroid drugs, and when the condition is serious, methotrexate, cyclophosphamide and other immunosuppressants can be used. The redness of the local skin of the nose is recommended to go to the hospital in time, the above drugs need to be used under the guidance of clinicians.