The majority of myotonic dystrophies have a poor prognosis and can eventually lead to disability and death of the affected child. At present, there is no cure, but mainly symptomatic and supportive treatment. Appropriate rehabilitative training and rehabilitation braces are used to support the limbs of the child to maintain and prolong the ability of the child to walk independently as much as possible. Small doses of corticosteroids can lower creatine phosphokinase levels, but cannot stop the progression of the disease. Gene replacement therapy and small molecule therapies such as antisense oligonucleotide-induced exon skipping are still in the experimental stage and are expected to improve the prognosis of the disease in the future. A balanced and nutritious diet is sufficient. Appropriate physical exercise to enhance resistance. For children with respiratory muscle involvement, respiratory tract infections should be avoided as much as possible and respiratory management should be strengthened when respiratory infections occur. As the disease is not curable, prenatal diagnosis to prevent the birth of such children is the most important prevention method. This test is now available in some hospitals in China that are qualified for prenatal diagnosis.