Aminophylline can directly relax the bronchial smooth muscle, inhibit the release of histamine and other allergic transmitters, and relieve the congestion and edema of the bronchial mucosa, which is one of the most commonly used asthma medications in clinical practice. The main indications for aminophylline are bronchial asthma, wheezing bronchitis, obstructive emphysema and dyspnea due to acute left heart failure.
The main dosage forms of aminophylline include aminophylline tablets and aminophylline injection, the indications, adverse effects and contraindications of the two dosage forms are the same, but the difference is that aminophylline injection has a faster and stronger effect, and its effect is slower and weaker compared with that of tablets.
Adverse drug reactions include nausea, vomiting, agitation, cardiac arrhythmia, which can lead to respiratory and cardiac arrest in severe cases, and is contraindicated in patients with drug allergies, active peptic ulcers, and uncontrolled convulsive disorders.
Improper use of aminophylline can easily lead to drug poisoning, which can be fatal in severe cases, so it is recommended that the drug be used in strict accordance with medical advice.