It is normal that the effect is not obvious after the first chemotherapy treatment for breast cancer. Chemotherapy is one of the more common treatments for breast cancer, and most patients need 4-6 courses of treatment to see obvious improvement, and it is not possible to see obvious effect in one treatment, that is to say, it is normal that the effect is not obvious after the first chemotherapy treatment for breast cancer, as long as the condition does not aggravate obviously, there is no need to worry about it too much. It is recommended to continue the current treatment after the first chemotherapy for breast cancer, and after the course of chemotherapy is finished, CT, blood routine and other tests will be carried out to judge the treatment effect. If the condition is still not relieved and improved, it is necessary to consider changing the treatment plan or treatment drugs, so as to avoid continuous deterioration of the condition. The patient’s sensitivity to chemotherapy and physical condition will affect the treatment effect, so it is recommended to follow the doctor’s instructions for continuous treatment.