Recombinant and inactivated vaccines are two commonly used forms of vaccines, both of which are widely used in clinical practice. Inactivated vaccine is a vaccine made by inactivating pathogenic microorganisms through physical or chemical means, so it is also called dead vaccine, while recombinant vaccine is made by recombinant antigenic components through genetic technology, and they are different in the following aspects: 1. The inactivated vaccine is a vaccine that uses physical means such as radiation or chemical means such as formaldehyde to treat the pathogen so that the pathogen loses viral activity but retains immunogenicity. In contrast, there are many recombinant vaccine preparation methods, such as recombinant protein vaccine technology, in which pathogen genes are inserted into non-pathogenic microorganisms and later transferred into other cells for reproduction and expression, and finally made into recombinant vaccines; 2. Different sources of antigens: Inactivated vaccine is a dead vaccine, which does not have the ability to reproduce in the body, mainly by generating antigens of pathogenic microorganisms and stimulating the immune cells, so that the organism appears The main purpose is to stimulate the immune cells by producing antigens of pathogenic microorganisms, so that the body can develop specific immune cells and thus achieve immunity. In contrast, recombinant vaccines mainly produce antigenic proteins through reproduction in other cells and are injected into the body to play an immunizing role; 3. The number of vaccination doses is different: inactivated vaccines usually require two doses with an interval of about 3 weeks; recombinant vaccines usually require three doses with an interval of about 4 weeks and above. Although recombinant vaccines and inactivated vaccines are slightly different, there is generally no significant difference in their effects, so it is not necessary to compare the advantages and disadvantages of the two, and you can choose according to your own situation to achieve the purpose of disease prevention.