A leukocyte esterase of 1 plus and 1 minus indicates the presence of neutrophils in the sample sent for testing, suggesting that the sender may have some indication of inflammation in the sample sent for testing. Leukocyte esterase is a specific enzyme contained in leukocytes and is generally found only in neutrophils and not in other body cells, so it can be used to test for the presence of neutrophils in a sample to make a determination about infection. If leukocyte esterase is plus, then it indicates inflammation but does not provide clarity on the specific type of pathogen, and vice versa for the absence of neutrophils in the specimen. A leukocyte esterase of 1 plus and 1 minus indicates that the test result is between normal and abnormal, and that inflammation may be present in the specimen sent for testing. In this case, patients should pay attention to rest, maintain sufficient sleep, pay attention to personal hygiene, change clothes diligently, and maintain a healthy diet, drink more water, eat more light food, such as green leafy vegetables, etc., so as to avoid aggravation of inflammation. Specific diagnosis and treatment, as well as the interpretation of indicators, should be carried out under the guidance of a physician.