1.The role of heat therapy? Microwave thermotherapy is a new heating device for clinical treatment of malignant tumors. Its action is in the form of a high-frequency interference current that causes the internal temperature of the tumor to reach 42℃, thus “killing cancer cells”. Microwave heat therapy has been used for local treatment of malignant tumors for more than 100 years, and its efficacy has been confirmed. Modern research also proves that heat therapy has direct cytotoxic effect, apoptosis effect, stimulating immune response, changing microcirculation in tumor and other mechanisms to kill tumor cells. 2.Why does the combination of heat therapy and chemotherapy have synergistic effects? In recent years, it has been found that the combination of heat therapy and chemotherapy has synergistic effects. Under high temperature, the membrane fluidity of cancer cells is increased, the permeability of tumor blood vessels is increased, and chemotherapeutic drugs enter and accumulate in cancer cells, which enhances the anti-cancer effect of chemotherapy. induced permeation and absorption, and increased cellular DNA damage. ②High temperature can inhibit the repair of DNA damage caused by chemotherapeutic drugs. ③Heating can increase the sensitivity of some chemotherapeutic drugs (such as platinum) to tumor cells. ④Heating acidifies the intracellular environment and promotes apoptosis caused by some chemotherapeutic drugs. ⑤Most chemotherapeutic drugs (such as DDP) can inhibit the accumulation of heat shock protein HSP. 3.What are the indications for heat therapy? It is used for all kinds of middle and late stage tumors, combined with radiotherapy and chemotherapy to increase the efficacy and prevent tumor recurrence and metastasis. It can play the role of palliative treatment for advanced tumors and can prolong the survival period. It is useful for cancerous thoracic ascites and pain 4. Contraindications to thermotherapy? (1) Severe cardiopulmonary dysfunction; (2) Severe liver and kidney failure; (3) Severe anemia and bleeding tendency; (4) Severe infection, sepsis and white blood cell count less than 2*109; (5) Intracranial infection caused by intracranial tumor and various new cerebrovascular diseases; (6) Recent surgical trauma has not healed; (7) Pregnant women and menstruating women are forbidden to do lower abdomen; (8) Heat therapy site has metal implants. implants. 5, heat therapy precautions? Wear thin cotton pajamas, bring a towel and water cup before heat therapy, and drink more water as appropriate. In heat therapy, communicate with the nurse in a timely manner to inform the discomfort reaction, prevent burns and dehydration. Dry your sweat after heat therapy to prevent colds. You may feel tired after heat therapy, so take more rest, drink more water, and rehydrate intravenously if necessary.