The test report of major triple-positive refers to positive hepatitis B surface antigen, positive hepatitis B E antigen and positive hepatitis B core antibody, which generally indicates that the virus replication is more active and more infectious. If the liver function is normal, the patient is a hepatitis B carrier, so the patient can be reviewed regularly. If the liver function is abnormal, especially if the transaminases are more than twice the upper limit of the normal value, antiviral treatment is needed. The current antiviral drug of choice is entecavir or tenofovir, which has a course of treatment of at least four years, and if there is cirrhosis, whether it is compensated cirrhosis or decompensated cirrhosis, its course of antiviral treatment is lifelong medication.