Atrophic gastritis C3 has the potential to become cancerous. Clinically, the appearance of atrophic gastritis C3 indicates that the degree of gastric mucosal atrophy is moderate, which is a more serious type of atrophic gastritis. If this condition is not treated in time, cancer may occur. Each patient’s physical condition is different, so the chance of cancer after developing atrophic gastritis C3 is also different. In order to prevent cancer, early treatment is needed, such as dietary modification and eating less cold, spicy and irritating foods. To address the cause of the disease, follow the principle of individualization to relieve symptoms and improve the histology of the gastric mucosa, and if combined with Helicobacter pylori, it is recommended to carry out the treatment of Helicobacter pylori eradication. During the treatment period, regular medical checkups are required to avoid complications.