Prednisone acetate tablets belong to the glucocorticoid class of drugs and are generally administered in a single dose at 7-8 am because the peak of human glucocorticoid secretion is between 8-10 am, and in order not to disrupt this rhythm, the administration of the drug needs to simulate the peak of human physiological secretion. If the drug is given in divided doses, it will have a significant inhibitory effect on the hypothalamus, pituitary gland and adrenal glands, while a single dose can greatly reduce and prevent the adverse consequences of hyperalgesia. Even if given once daily, long-term use of hormonal drugs can cause many adverse effects, such as elevated blood pressure and blood glucose, and lowered blood potassium and calcium. Therefore, hormonal drugs must be used properly under the guidance of a specialist and gradually reduced, and blood pressure and blood glucose should be monitored and calcium and potassium tablets should be supplemented during the medication period.