Nitroglycerin is available in injectable and oral tablet forms and is a prescription drug. It is mainly for patients suffering from coronary heart disease and angina pectoris, and can be used in the clinical treatment of patients with heart failure, and has the effect of lowering blood pressure. Clinical use should grasp the indications, and it is prohibited to be used in patients with severe anemia, glaucoma and allergy to nitroglycerin. Some patients may experience adverse reactions during the use of the drug, such as nausea, vomiting, sweating, pallor, deficiency, headache, sudden fainting, and drug rash when standing after using the drug. Nitroglycerin is commonly used in the treatment of patients with cardiovascular diseases. Adverse reactions may occur with improper use and require a doctor’s prescription based on the condition and use under medical supervision.