There is no definite time for how long it takes to get well from leukemia transplantation, the exact recovery time varies with different types of transplants, as well as with the number of post-transplantation complications, which is about 3 months to 1 year. 1. Autologous hematopoietic stem cell transplantation: no need to use immunosuppressive drugs, good recovery of hematopoietic function, good health condition, the time needed to return to normal is shorter, usually it takes 3 to 6 months to return to normal. 2. Allogeneic hematopoietic stem cell transplantation: immunosuppressive drugs such as tacrolimus are needed to prevent transplant rejection and graft-versus-host disease. It takes at least 6 to 12 months for allogeneic transplant patients who are compatible with each other to return to normal, and at least 1 year for allogeneic transplant patients who are incompatible with each other to recover. When complications such as graft failure, graft rejection, or post-transplant relapse occur, a second transplant may be required, thus requiring even longer time for recovery. If you feel unwell after leukemia transplantation, you should go to the hospital for consultation to clarify the cause and receive targeted treatment under the guidance of your physician.