Why are some glaucoma cases not diagnosed after a complete set of tests? Glaucoma is essentially a chronic optic neuropathy. In the early stages, when optic neuropathy is not typical, it may be confused with high myopia, other causes of optic nerve changes, or simple hypertension. Therefore, the diagnosis may not be confirmed after all the tests are done, but your doctor will assess your risk of glaucoma based on the results of the tests. How often do I need to be rechecked for undiagnosed suspected glaucoma? For undiagnosed suspected glaucoma, the doctor will need to assess the number of risk factors. If the risk is very high, you can review it in about three months, and if the risk is average, you can review it in about six months. If the risk is relatively low, you can choose to review once a year. What is found at the review that confirms the diagnosis? Because glaucoma is a progressive disease, the diagnosis can be confirmed if the optic nerve damage appears to progress similar to glaucoma. Typical glaucomatous changes in the optic nerve or visual field appear during follow-up, or are more pronounced than those suspected on previous reviews, such as localized thinning of the optic nerve fibers and defects in the optic disc. If there is no conclusive evidence of glaucoma, is it time to stop the review? If there is no conclusive evidence for three consecutive years, and the doctor assesses the risk of glaucoma to be low, it can be extended to 3-5 years for glaucoma screening. If the risk is assessed to be high, it still needs to be reviewed once every 1-2 years. We have seen patients clinically who have gone from suspected glaucoma to a final diagnosis of more than 10 years. What is a glaucoma provocation test? How does it help to confirm the diagnosis? Who is it for? Are there any risks? Glaucoma provocation tests, including the water test, dark room prone, and dilated pupil provocation tests, are being used less and less in clinical practice because of the risks involved and because modern technology has brought more reliable methods of examination and evaluation. Is it possible to start medication for suspected glaucoma without a confirmed diagnosis? For patients with suspected glaucoma, with a relatively high degree of elevated intraocular pressure, or with a relatively high assessed combined risk and a young age, we can choose medication to lower the intraocular pressure and reduce the risk of serious optic nerve damage.