Low estradiol, which is also known as low estrogen, represents a decline in ovarian function, and may also represent ovarian diseases, endocrine disorders and other disorders. Estrogen changes cyclically with women’s age. For example, if the ovarian function of women over 40 years old gradually declines, there will be a decline in estrogen, which is a normal physiological phenomenon. Endocrine disorders caused by excessive dieting, overeating and other reasons, as well as ovarian diseases, diabetes and other diseases can also lead to low estrogen. If low estrogen is detected in the examination, it is necessary to go to the hospital in time, and carry out targeted treatment after perfecting the examination. If it is caused by diseases, we need to treat the primary disease, and if necessary, follow the doctor’s instructions to supplement estrogen and maintain ovarian function. Low estrogen, it is recommended that timely and clear examination and treatment, to avoid the adverse effects of self-supplementation of estrogen.