When children develop perioral dermatitis, the cause needs to be identified, which may be caused by perioral acne, tongue licking dermatitis and other diseases, with different causes and different treatments, and the main treatments are general care, medication and so on. If the dermatitis is caused by perioral acne, children need to keep the skin clean, eat more fresh fruits and vegetables, and do not frequently stimulate the acne area. If necessary, topical medications such as erythromycin and lincomycin can be used for treatment, or medications such as isotretinoin can be given orally. In addition, tongue licking dermatitis is a kind of contact dermatitis caused by children repeatedly licking the skin around the mouth with their tongues, to correct the children’s bad habits of lip licking, drink more water, eat more vitamin-rich fruits and vegetables, etc., if necessary, can be under the guidance of the doctor, topical topical erythromycin ointment, tacrolimus ointment and so on. There are many other reasons that can cause perioral dermatitis, should be timely consultation, to identify the cause, and by the doctor to give targeted treatment. The medication should be used in accordance with the doctor’s instructions.