Overview
Dengue filariasis is caused by erythematous Dengue filariasis infection, the most frequent clinical manifestation is often Dengue-like type, which is an acute but slow progressing skin disease. It is an acute but progressive skin disease. Remove predisposing factors, actively treat the primary lesion, and provide appropriate supportive therapy, such as antibiotics, if systemic symptoms appear or are severe. Good personal protection is the key to preventing this disease.
Causes
Erysipelas erythematosus (formerly known as Cryptosporidium erythematosus) is a gram-positive, pod-less, non-budding cell-forming, inactive, microaerophilic bacillus with a worldwide distribution. It is primarily saprophytic, however it can infect a wide variety of living animals including insects, shellfish, fish, birds and mammals (especially pigs). Infection in humans is mainly occupational, typically contracted from puncture wounds when handling edible or inedible animals by hand, such as infected animal carcasses, extracted products (tallow, fertilizers), bones, and shells; non-dermal infections are rare, and are usually accompanied by arthritis and endocarditis.
Symptoms
The most frequent clinical manifestations are often of the dengue-like type, which is an acute but slowly progressive skin disease. There is itching without tenderness and no systemic symptoms. The erythema is ill-defined and deeply infiltrated, and suppuration is evident. Angioedema occurs in areas of sparse tissue, and the damage is edematous with indistinct margins and no tenderness. It can be complicated with Danovan filamentous arthritis and Danovan filamentous endocarditis.
Examination
1. Biopsy
Thick skin slice culture for isolation of erythematous filamentous bacilli is better than culture of needle aspirates at the extended margin of the lesion, and culture of exudates obtained from abraded bright red papules is also of diagnostic value.
2. Bacterial isolation test
In order to diagnose Danovan filamentous arthritis or endocarditis, it is necessary to isolate bacteria from blood or synovial fluid.
3. Polymerase chain reaction (PCR) amplification test
PCR amplification of the DNA sequence encoding 16srRNA of D. erythematosus is useful for rapid diagnosis.
Diagnosis
Diagnosis is confirmed on the basis of etiology, clinical presentation and the above mentioned investigational data.
Differential diagnosis
1. Contact dermatitis
History of contact, itching without tenderness, no systemic symptoms.
2. Cellulitis
The redness and swelling are not clear, the infiltration is deep, and the suppuration is obvious.
3. Angioedema
Prevalent in loose tissues, the damage is edematous with unclear margins and no tenderness.
Treatment
1. Systemic treatment
Remove the triggering factors, actively treat the primary lesions, if there are systemic symptoms or severe manifestations should be given appropriate supportive therapy, such as antibiotic therapy.
(1) Penicillin Penicillin should be injected intravenously or intramuscularly for about 2 weeks.
(2) Benzathine penicillin Intramuscular or erythromycin orally, 4 times a day for 7 days can cure.
(3) Sulfonamides or other antibiotics.
2. Local treatment
Anti-inflammatory. Local can use a variety of antibiotic ointment dandruff ointment, 20% ichthyol ointment or pure ichthyol paste. The area around the affected part can be coated with 2% tincture of iodine or 0.1% ethacridine (levano) solution wet compresses.
In cases of tinea pedis and varicose veins of the lower extremities, helium-neon laser, ultraviolet light and superficial X-ray are effective, and local injection of streptococcal antitoxin can prevent recurrence.
In cases of endocarditis or arthritis, cefazolin can be used.
Prevention
Anyone who has access to meat or fish contaminated with Streptococcus, such as slaughterers, meat processors, herders, fishermen, fish processors, cooks, food handlers, etc., may be infected, so good personal protection is the key to preventing the disease.