Cold, cough and runny nose medication is not effective may be because the drug is ineffective, you need to consult a doctor in time for examination and treatment. For coughing and sniffling, you can take oral phenmetrazine, pseudoephedrine and other cold medicines; if it is combined or secondary bacterial infection, you need to take antibiotics, such as amoxicillin, roxithromycin and so on, in accordance with medical advice. Cold has self-limiting, mild symptoms can not take drugs, pay attention to rest, light diet can be; obvious symptoms can be symptomatic medication, such as nasal congestion, runny nose, etc., you can take phenmetrazine, pseudoephedrine and other medications; if there is a fever, generalized pain, the need for antipyretic and analgesic, such as acetaminophen, ibuprofen and so on. The common cold usually requires no special antiviral treatment; if it is combined with or secondary to a bacterial infection, antibiotics, such as roxithromycin and amoxicillin, need to be taken as prescribed by the doctor. If you have a cough and runny nose, you should consult a doctor for a clear diagnosis and guidance for further treatment, and should not delay your condition by treating it on your own.