The concept of large neck disease often refers to an enlarged thyroid gland. There are more reasons for enlarged thyroid gland, as follows: 1, hyperthyroidism can also cause large neck; 2, hypothyroidism, also manifested as large neck; 3, thyroiditis, especially immune, such as Hashimoto’s thyroiditis, also manifests as enlarged thyroid gland and large neck disease; 4, thyroid nodules, thyroid cysts, thyroid tumors can manifest as large neck and enlarged thyroid gland. If you have a large neck, you must go to the hospital for relevant examinations, including functional measurement of the thyroid gland, thyroid ultrasound, and thyroid CT examination. We can determine what causes the big neck from both functional and morphological aspects, so that we can come up with a treatment plan, whether it is surgery or medication.