For metastatic adenocarcinoma with unknown primary foci, first of all, surgical resection or radiotherapy should be carried out for the metastatic foci to control the cancer cells, and at the same time, regular checkups should be carried out to find out the primary foci for treatment of the cause of the disease. 1. Treatment of metastatic foci: metastatic adenocarcinoma refers to the cancer that has metastasized from the primary lesion to the gland or glandular epithelial area, which belongs to cancers with higher malignant degree. After metastatic adenocarcinoma appears, it is generally recommended to perform surgical resection as early as possible to effectively remove the metastatic tumor, and cooperate with radiotherapy to control the spread of cancer cells in the metastatic area or secondary metastasis. 2. Regular examination: Removing the primary lesion is more important for treating metastatic tumor. Therefore, when the primary lesion is not clear, it is recommended to carry out regular checkups of blood system, lymph and bones when treating metastatic tumors, which can help determine the primary site so as to carry out causative treatment as early as possible. In the process of metastatic adenocarcinoma tumor treatment, it is recommended to cooperate with doctors for regular treatment and take appropriate nutrition to effectively strengthen the body.