Neuroblastoma usually has no precursor, and its early clinical manifestations include vomiting, fatigue, and generalized pain, etc. Some patients also have cough and diarrhea. Neuroblastoma is a common malignant tumor in infants and children, and most of the patients with neuroblastoma do not have obvious precursors, and some of them may have some symptoms in early stage, such as diarrhea, abdominal pain, coughing, vomiting, and generalized pain, etc. It should be noted that some patients may have diarrhea, abdominal pain, weakness and generalized pain. It should be noted that some patients with diarrhea, cough and other symptoms are easy to be misdiagnosed and delay the best time for treatment, which makes the symptoms worse, therefore, when the above symptoms are suspected to be neuroblastoma, they should be sent to the hospital in time, and be diagnosed and treated under the guidance of the doctor, so as to avoid delaying the condition.