If a patient taking Metformin develops signs of yin deficiency and fire exuberance (deficiency of yin and essence in the body, resulting in hyperactive fire), he or she can take Zhi Bai Di Huang Wan as prescribed by the doctor. Metformin is a non-insulin hypoglycemic drug used in the treatment of type 2 diabetes; Zhi Bai Di Huang Wan belongs to the category of tonic Chinese medicines, which has the effect of nourishing yin and lowering fire (nourishing the yin essence and lowering the fire). Metformin, a biguanide hypoglycemic drug. Zhi Bai Di Huang Wan, composed of Zhi Mu, Huang Bai, Shu Di Huang and Shan Zhu. It has the effect of nourishing yin and lowering fire, and is used in treating yin deficiency and fire exuberance, hot flashes (a burst of fever), night sweating (abnormal sweating after going to sleep, but sweating stops after waking up), dry mouth and sore throat, tinnitus, spermatorrhea, and short and red urination (small amount of urination, dark yellow in color), etc. It is also used in treating heat deficiency and actual heat. Caution should be exercised in cases of Qi deficiency with fever and actual fever; caution should be exercised in cases of cold and flu. It is recommended to use the medicine under the guidance of a professional physician.