Phagocytosis syndrome after three platelet transfusions and dropped to more than twenty can be relieved by general treatment, drug treatment and surgical treatment. 1. General treatment: acute bleeding patients continue to transfuse platelets, fresh frozen plasma, prothrombin complex, etc., and supplement coagulation factors when necessary. Recombinant human thrombopoietin can also improve the level of platelet count. 2. Drug therapy: use induction therapy as soon as possible after exclusion of contraindications, available drugs such as dexamethasone, etoposide, etc. When central nervous system is involved, intrathecal injection of drugs such as methotrexate and dexamethasone can be given as early as possible when the condition permits. 3. Surgical treatment: patients with recurrent refractory hemophagocytic syndrome and central nervous system involvement can choose allogeneic hematopoietic stem cell transplantation. The hemophagocytic syndrome after three platelet transfusions and down to more than twenty may have other treatment methods, such as secondary to other diseases such as infection, lymphoma, rheumatoid arthritis, etc. should also be actively treating the primary pathology. It is recommended to standardize the treatment under the guidance of the doctor. All of the above drugs should be used reasonably under the guidance of a doctor, avoid self-medication.