Yellow skin may be related to impaired liver function, anemia, hemolytic jaundice and other factors, and may also be related to food, medication, and prolonged late-night and other factors. 1. Impaired liver function: when liver function is impaired due to various reasons, the metabolism of bilirubin by the liver is impaired, which can be manifested as yellowing of the skin and mucous membranes as well as the sclera. 2. Anemia: when there is a lot of bleeding or other reasons lead to severe anemia, it will also be manifested as pale or yellow skin, and may be accompanied by dizziness, fatigue and other phenomena. 3. Hemolytic jaundice: a large number of red blood cells in the blood are destroyed, producing a large amount of unconjugated bilirubin, which is not metabolized by the liver cells in time, and will accumulate in the body and cause jaundice, which can be manifested as yellowish staining of the skin, mucous membranes and sclera. 4. Food factor: taking too much carotene-rich food in a short period of time may lead to yellowing of the skin of the palms of the hands and the skin of the face, such as carrots, oranges and so on. 5. Drug factors: long-term use of certain drugs can lead to yellowing of the skin, such as furotoxin, furazolidone and so on. 6. In addition, excessive late night and sleep deprivation in daily life will also make the skin yellowing phenomenon. As the yellowing of the skin affects many factors, it is recommended to go to the hospital in a timely manner to clarify the cause and follow the doctor’s instructions for treatment.