The birthmark of café au lait is a kind of pigmented patch, and there are different treatment methods according to the characteristics of the birthmark and the growth area. If the birthmark of coffee spot grows on the trunk with unclear border or light color, the birthmark does not affect health, but because the coffee spot will not fade by itself, and there may be neurofibroma when it is larger, so you should seek medical attention and temporarily withhold treatment after doctor’s evaluation, but you should pay attention not to scratch repeatedly with nails to prevent infectious dermatitis and pay attention to observation. If the color of birthmark is darker, you can choose to use medication, including external use of creams with bleaching function, such as azelaic acid cream or thousand white hydroquinone cream, and also choose to take vitamin C or glutathione orally for treatment, but medication is generally less effective and takes longer time. If the border of birthmark is clearer and the color is darker, laser treatment such as fractional laser or excimer laser can be carried out and oral medication can be taken at the same time, and the pigment can basically disappear after the scab produced by the laser falls off. Usually, laser treatment is effective, but recurrence may occur and multiple treatments are needed, and sun protection should be strengthened during treatment. For single coffee spot birthmark growing on the face, it can also be treated by surgery, but the surgery has certain risks and may leave scars.