Dulcolax, or pethidine hydrochloride, is a synthetic opioid receptor agonist, a phenylpiperidine derivative, a synthetic analgesic for clinical application, a white crystalline powder with addictive properties. Dulcolax, as a strong analgesic drug, can be applied to various analgesics, such as traumatic pain, cancer pain, and visceral colic, but the analgesic effect is weaker than morphine. There is no oral form of Dulcolax, and repeated intramuscular injections may cause local inflammation of muscle soft tissues, or lead to local formation of hard nodes, or even cause heavy fibrosis of muscle tissues. Patients are prone to a floating sensation after Dulcolax injection. Long-term use of Dulcolax is addictive and can easily lead to psychiatric symptoms in patients and can result in a situation where the analgesic effect is significantly weakened. The metabolite of dulcolax is norethindrone, which has a weak analgesic effect and strong neurotoxicity. Long-term use can lead to clinical symptoms such as tremors, spasms and convulsions, so dulcolax is less often used in clinical practice.