Urease is a product of H. pylori metabolism, and the presence or absence of H. pylori infection can be clarified by testing for antibodies to urease. Therefore, a positive H. pylori urease antibody test indicates the presence of H. pylori infection in the body, and further carbon 13 or carbon 14 breath tests are required to clarify the diagnosis. H. pylori infection can lead to gastritis, gastric ulcer and other lesions, and gastrointestinal symptoms such as epigastric pain, acid reflux and belching, which can transform from gastritis and gastric ulcer to gastric cancer if left untreated. Therefore, it is very important to eradicate H. pylori. A combination of bismuth, a proton pump inhibitor, and two antibiotics is usually used in a quadruple therapy. In eradication therapy, patients should take the medication regularly until H. pylori is eradicated, and then undergo a urease breath test 1 month after treatment to determine whether it is completely eradicated. During the treatment period, you should also pay attention to the regularity of life, combine work and rest, avoid overwork and mental tension, chew slowly, do not eat spicy food, do not drink strong tea, coffee, wine and stimulating drinks, and quit smoking. Wash your hands before and after meals, and do not eat raw meat or drink cold water.