H. pylori is a parasite in the human body and is infectious. It is usually transmitted through the digestive tract, including the fecal-oral route and the oral-oral route. Kissing is one of the oral-oral routes, in which H. pylori can be transmitted to healthy people through contact with the saliva of an infected person, leading to infection. After kissing a patient with H. pylori, you should go to the hospital for examination in time to avoid delaying the disease. If the result of the first inquiry is not abnormal, you can wait 1-2 weeks for a follow-up examination to confirm. If H. pylori infection is detected, “bismuth quadruple” is currently recommended as the main empirical H. pylori eradication regimen. Bismuth quadruplex is a combination of 1 bismuth + 1 proton pump inhibitor (PPI) + 2 antibiotics to control the progression of H. pylori infection and to kill H. pylori. Patients who are positive for H. pylori should preferably use dishes independently, practice meal sharing, and be well protected to avoid cross infection. Sneezing or coughing at others should be avoided in daily life to avoid transmission through respiratory droplets. Wash your hands before and after meals, and actively seek medical treatment to avoid delaying the development of gastritis, peptic ulcer, gastric cancer and other diseases.