There are two possibilities for increased antibodies to H. pylori, including present infection or previous infection, and the specific causes and treatments are as follows: 1. Present infection: whether treatment is needed depends on the specific number of H. pylori infections and symptomatic manifestations. If the H. pylori measurement value <100dpm/mmol, and there is no nausea, acid reflux, vomiting, stomach pain, upper abdominal discomfort and other gastric disease performance, can be considered without any treatment, continue clinical observation can be. If the H. pylori measurement value is >100dpm/mmol, or if there are already obvious symptoms of gastric discomfort, medication is required at this time. A quadruple anti-H. pylori drug is commonly used in clinical practice, i.e. two antibiotics, a proton pump inhibitor, and a bismuth agent, to ensure the therapeutic effect and at the same time protect the gastric mucosa. If the condition recurs, additional second-line class anti-H. pylori drugs such as levofloxacin and quinolone are also needed; 2, ever infected: ever infected can also lead to increased antibodies to H. pylori, but if it is not clear whether the infection is now, it can be further confirmed by other tests, such as carbon 13 or carbon 14 breath test, gastroscopy, urease and other tests to determine. If the current infection is clear, treatment can be administered according to the course of treatment, or if there is no infection, no treatment is needed and clinical observation is sufficient.