The main symptoms of tetanus include prodromal symptoms, persistent muscle contraction, and other symptoms, which usually do not cause edema. 1. Prodromal symptoms: in the early stage of the disease, patients may experience weakness, dizziness, excessive sweating, difficulty in opening the mouth, soreness of the biting muscle and other symptoms, which usually do not cause edema, and such symptoms are not specific, and it is difficult to distinguish them from other diseases. 2. Continuous muscle contraction: with the development of the disease, the symptoms of continuous muscle contraction can occur. From the chewing muscles to the facial muscles, neck muscles, and even the limb muscles, the symptoms of continuous contraction. Typical “bitter smile face” and “angular retrusion” may appear. 3. Other symptoms: During the seizure, the patient may also experience rapid heartbeat, shortness of breath, profuse sweating, muscle spasm and other symptoms. In the later stage, pulmonary atelectasis, lung infection, heart failure and even asphyxiation may occur, and the patient may die as a result. Therefore, attention should be paid to the prevention of tetanus after trauma.