Whether the patient needs to play tetanus after being cut by a knife, according to the different severity of local damage, whether the knife is clean and other factors for objective analysis: 1, if the patient’s hand is cut by a knife is very superficial, only accompanied by skin cuticle damage, local and no active bleeding. If the patient’s hand is cut by a knife is relatively clean and there is no more rust, the patient may not need to inject tetanus antitoxin or tetanus immunoglobulin, but only need to use 0.5% vital iodine cotton ball local disinfection, sterile gauze bandage, can achieve better treatment results. 2, if the patient’s hand is cut by a knife is deeper, local with active bleeding, and the knife cut hand with more rust. At this time, it is recommended that patients within 24 hours of injury, timely injection of tetanus antitoxin or tetanus immunoglobulin, so as not to cause tetanus infection.