Immunoglobulin (immunoglobulin) refers to animal proteins with antibody activity. It is mainly found in blood plasma, but also in other body fluids, tissues and some secretory fluids. The normal range of serum immunoglobulin (Ig) includes: IgG, IgA, IgM, IgD, IgE. its normal range: IgG 7,6~16,6g/L; IgA 0,71~3,35g/L; IgM 0,48~2,12g/L; IgD 0,01~0,04g/L; IgE 0,001~0,009g/L. Then, the patient’s serum immunoglobulin may be elevated. Globulin can be elevated, what other tests should be done? The following is a brief introduction: 1. Blood routine: blood routine is the most general and basic blood test. Routine blood tests are usually performed with peripheral blood, such as blood from the fingertips and earlobes. After the blood cell analysis instrument, the computer reports the results, and this item has become a practice to examine patients. Blood consists of two major parts, liquid and tangible cells, and routine blood tests are performed on the cellular part of the blood. Blood has three different functions of cells – red blood cells (commonly known as red blood cells), white blood cells (commonly known as white blood cells), and platelets. Diseases are determined by observing changes in number and morphological distribution. It is one of the common auxiliary tests used by doctors to diagnose the condition. 2, guanosine cyclic phosphate: guanosine cyclic phosphate is widely distributed in various tissues, and its content is about 1/10 to 1/100 of cAMP, which is generated by GTP catalyzed by guanylate cyclase and decomposed by phosphodiesterase. cGMP has the opposite effect of cAMP, cGMP has the effect of acetylcholine, inhibits myocardial contractility, reduces heart rate, increases neuroexcitability, stimulates the release of leukocyte lysosomes hydrolytic enzymes, stimulate lymphocyte division and proliferation, inhibit gluconeogenesis and excite parasympathetic function. 3.Mixed lymphocyte culture test: Mixed lymphocyteculture (MLC) is a test to determine the compatibility of major histocompatibility antigens (HLA antigens) of the recipient and donor, and is commonly used for tissue matching before organ transplantation. Mixed lymphocyte culture is a test in which donor and recipient lymphocytes are mixed in both directions, or inactivated donor lymphocytes are mixed in both directions, and the degree of cellular response is negatively correlated with the degree of donor-recipient compatibility.