There is no one best method for gallstones pain relief in the clinic, each patient’s physique and condition are different, and the one that suits you is the best. Gallstones pain relief can be treated through general treatment, drug treatment, surgical treatment and other methods. ⒈ general treatment: for most asymptomatic gallstone patients, generally need to adjust the diet and lifestyle, usually pay attention to avoid excessive mental stress, regular diet, avoid overeating, less greasy food, and increase the amount of exercise, enhance immunity, and regular checkups in the hospital. PEAK medication: If gallstones patients are in acute attacks when the pain is more pronounced, you can take medication for analgesia, such as diclofenac, pethidine, etc.; if the patient has chills, fever conditions and other symptoms of infection, you can take cefoperazone, moxifloxacin and other anti-infective drugs. ③Surgical treatment: patients with gallbladder stones can prefer minimally invasive laparoscopic cholecystectomy for treatment; patients with bile duct stones can choose laparoscopic choledochotomy combined with cholecystectomy, or endoscopic retrograde pancreatic cholangio-pancreatic extraction and endoscopic sphincterotomy to remove stones. When diagnosed with gallstones, go to the hospital for consultation and treatment in time to avoid delays.