Local burning and pain in the anus is mainly caused by local inflammatory irritation of the skin and mucosa or acute attacks of hemorrhoidal edema. Inflammatory changes of the intestinal mucosa are mainly seen in local mucosal rupture of the anus after acute diarrhea, inflammation of the anal canal and rectum, and acute attacks of perianal abscess and anal fistula. If the local mucosa is burning and painful due to acute diarrhea, oral antidiarrheal drugs can be taken and erythromycin ointment can be applied locally to the anus for anti-inflammatory treatment. If it is accompanied by anal canal inflammation or proctitis, you can choose to anally insert metronidazole suppositories or herbal retention enemas. If it is accompanied by local mucosal erosion and bleeding, you can also add Yunnan Baiyao capsule powder or tin type dispersion to the enema. Acute attacks of perianal abscesses or fistulas that cause severe perianal pain require surgery as soon as possible. If the hemorrhoid edema or blood clot causes local burning pain in the anus, you can choose to apply hemorrhoid cream or operate directly.