The symptoms of sneezing and runny nose can be seen in both common cold and influenza. Both common cold and influenza are upper respiratory tract diseases caused by viral infections. The common cold is characterized by upper respiratory symptoms, such as sneezing, nasal congestion and runny nose, and mild systemic symptoms. Influenza is characterized by systemic symptoms, such as high fever, aching limbs and fatigue, while sneezing, nasal congestion and runny nose are mild. Both common cold and influenza can have sneezing and runny nose symptoms, but the nasal mucus is usually clear water nasal mucus or white sticky nasal mucus. If there is a secondary bacterial infection, symptoms of runny nose may occur. The common cold is a self-limiting illness that usually resolves itself without treatment. If the symptoms of nasal congestion and runny nose are severe, nasal mucosal decongestants such as ephedrine drops can be used to relieve the symptoms. If there is a runny nose, antibiotics such as amoxicillin and cefixime can be used to fight infection. Influenza requires antiviral drugs such as oseltamivir in addition to symptomatic and anti-infective treatment. In addition to this, runny nose and sneezing are also common in allergic rhinitis, which can be relieved with antihistamines such as cetirizine or glucocorticoids such as budesonide nasal spray. If there is a runny nose, antibiotics such as amoxicillin and cefixime should be used to treat the infection. Sneezing and runny nose can also be caused by other diseases, if the symptoms are not relieved or aggravated, it is recommended to consult a doctor in time, improve the examination, clarify the cause of the disease, and standardize the treatment under the guidance of the doctor.