The thickening of the liver spots should be noted, and it should be clarified what causes the thickening of the liver spots, generally seen in viral hepatitis, fatty liver and autoimmune liver disease. 1. Viral hepatitis: such as hepatitis B and hepatitis C, in the early stage, b ultrasound can not be observed under the changes, when there is a liver spot indicates that the liver is damaged or diffuse lesions, hepatitis viruses can lead to inflammation of the liver, and even fibrosis, the patient often appear abdominal distension, fatigue. 2. Fatty liver: Fatty liver is a diffuse lesion that occurs in the liver when too much fat is accumulated in the liver, which affects the normal function of the liver, and its evolutionary process will lead to cirrhosis, which affects the normal physiological functions of the liver, such as the production of bile. 3. Autoimmune liver disease: this is a liver disease due to autoimmune factors, causing hepatocellular damage, there will be pressure pain of the liver, splenomegaly, spider nevus in the early stage, to the stage of cirrhosis may also appear in the esophagogastric fundus vein bleeding. Therefore, for liver light spot thickening to clarify the specific situation, according to the different causes of different treatments, if there is discomfort, timely medical treatment, to avoid the development of the disease.