The normal value of anti-thyroglobulin antibody (TgAb) should be less than 60IU/ml, the specific reference value range may vary according to different testing methods. For pregnant women, TgAb tends to decrease with the progress of pregnancy, and then rebound to increase after delivery, the specific reference value can be consulted with the doctor. TgAb is a common autoantibody in the serum of patients with autoimmune thyroid disease. It has clinical value in the regression and treatment of thyroiditis, especially Hashimoto’s thyroiditis. The normal value of TgAb should be less than 60 IU/ml, and the specific reference range may vary according to different testing methods. In normal women, the positive detection rate of TgAb increases with age, which may be an early response to autoimmune thyroid disease. In pregnant women, TgAb tends to decrease with the course of pregnancy and rebound to increase after delivery. Pregnant women with abnormal antithyroglobulin antibodies should go to the hospital in time and be treated under doctor’s supervision.