The differences between glutamine and vitamin B1 are as follows: First, glutamine cannot be taken for a long time, while vitamin B1 can be taken for a long time because vitamin B1 is a water-soluble vitamin, and long-term or overdose will not cause toxic side effects and uncomfortable reactions to people because the water-soluble vitamin can be metabolized and decomposed by the body and excreted. Glutathione is a combined lipid of ferulic acid and biosterol, which will lead to side effects when taken for a long time and make patients suffer from indigestion, bloating, abdominal pain and other uncomfortable symptoms. Second, the direction of treatment is different, although glutamine and vitamin B1 can treat brain neurasthenia and have the role of promoting sleep, but the main role of vitamin B1 is to nourish the nerves, while the main role of glutamine is to regulate plant nerve disorders and endocrine disorders, so their pharmacological effects are different.