Statin generally refers to statin drugs, which mainly have the effect of lowering blood lipids. Regular consumption of statins (such as atorvastatin, etc.) may lead to impaired liver function, rhabdomyolysis, gastrointestinal reactions, etc., which need to be analyzed specifically. 1. Impaired liver function: long-term oral statin drugs may cause transaminase elevation, most patients can slowly recover after stopping the drug, but some patients will have liver function abnormalities and other symptoms, it is recommended to check the liver function every 3 months to clarify the use of drugs. 2. Rhabdomyolysis: a very small number of patients with unexplained muscle pain and discomfort, muscle tenderness, stiffness or spasm, etc., found that the rhabdomyolysis, creatine kinase, lactate dehydrogenase and other muscle enzymes are elevated. 3. Gastrointestinal reactions: long-term application of statins may lead to gastrointestinal reactions such as nausea, vomiting, constipation and so on. If patients need to take statins for a long time, they need to follow the doctor’s instructions, not to increase the dose privately, and to go to the hospital regularly for review.