In neurosurgery, we often come across some patients with cranial defects, some of them have cranial defects caused by traffic accidents, and some of them have craniotomy because of craniocerebral diseases, and left cranial defects, and no matter what the reason is, the impact of cranial defects is very great, and the patients should pay attention to it. Because the skull defect, the cranial cavity is no longer intact, the brain tissue lacks an external protective barrier, intracranial pressure and intracranial environment will become very unstable, if not repaired will lead to a series of cranial defect syndrome, such as patients will have dizziness and headache symptoms. Can dizziness and headache be treated with cranial bone repair surgery? For patients with large cranial defects, it is recommended to have cranial repair surgery in time, so as to rebuild a closed and complete cranial cavity environment, in order to ensure the safety of intracranial tissues as well as the normal operation of the brain and nerve function. However, it is important to choose a good repair material, which is a key factor affecting the success or failure of the surgery. Nowadays, titanium mesh material is widely used in many hospitals, but because it is a metal material, the overlay repair method used will cause some problems and deficiencies after the surgery, such as possible infection and rejection after the surgery, cutting pain for patients and sensitivity to external hot and cold environments, and so on. The PEEK material used by our team now avoids these problems, it is a very advanced polymer material, its performance is very good, the use of embedded repair method, and we also introduced the concept of aesthetic plastic surgery, so that the postoperative appearance is more natural and good-looking.