Gastrin can increase the secretion of gastric acid, pepsin, pancreatic juice, etc.; can enhance the contractility of the stomach, small intestine, colon, gallbladder; relax the pylorus, biliary orifice and ileocecal sphincter; promote the release of insulin and calcitonin.
Gastrin is also known as gastrin, gastrin promoter; the fluctuation range of normal human serum gastrin is 20~160ng/L; it is a gastrointestinal hormone secreted by the gastric sinus and duodenum, and it has a variety of physiological functions, such as promoting the autoregulatory secretion of gastric acid and nourishing the mucous membranes of the gastrointestinal tract.
Gastrin can increase the secretion of gastric acid, pepsin, pancreatic juice, pancreatic secretin, and water and salt in bile; enhance the contractility of the stomach, small intestine, colon, and gallbladder, and increase the tension of the lower esophageal sphincter to maintain the high pressure band at the esophageal cardia; relax the pyloric sphincter, the sphincter of the biliary orifice, and the sphincter of the ileocecal sac; nourish the gastric and duodenal mucosa; and promote the release of insulin and calcitonin.
Abnormally elevated gastrin: common in gastrinoma, excessive formation of sinus mucosa, chronic renal insufficiency, gastric and duodenal ulcers, type A atrophic gastritis, vagotomy, and hyperthyroidism.
Abnormally lowered gastrin: common in gastroesophageal reflux, type B atrophic gastritis, hypothyroidism, and gastric sinus cancer.
Normally, we should develop good living habits and dietary habits, pay attention to light and regular meals, do not eat greasy and spicy food, avoid overeating; when abnormal secretion of gastrin is found, we should consult the doctor in time.