Total protein is the sum of albumin and globulin in plasma, with a normal range of 60-80 g/L. Normally, total protein in the body is rarely significantly elevated. If it does increase, it is mainly due to an increase in globulin. If total protein, albumin and globulin are increased at the same time. The most common reason is that the concentration of blood leads to an increase in the concentration of total protein, albumin and globulin. For example, after severe dehydration, such as severe vomiting, diarrhea, dehydration after a lot of exercise, as well as people with adrenocortical hypoplasia, the three kinds of protein can be increased at the same time. Secondly, patients with increased globulin can cause an increase in total protein, but albumin is usually normal, and then if dehydration occurs, total protein, albumin, and globulin can also increase at the same time, so the three kinds of proteins increase at the same time, which is mainly seen in a variety of severe dehydrating diseases.