Clopidogrel can be taken by patients with atrial fibrillation if there are no contraindications and no adverse effects after taking it. Clopidogrel is an antiplatelet drug. It prevents platelets (a type of blood cell) from aggregating and forming blood clots that can lead to a heart attack or stroke. In patients with atrial fibrillation, clopidogrel alone or with aspirin can prevent blood clots. It prevents diseases such as cerebral infarction or myocardial infarction from occurring in patients with atrial fibrillation due to the formation of blood clots or dislodgment of blood clots. Clopidogrel should not be taken if the patient has contraindications such as coagulation abnormalities, increased risk of bleeding due to trauma, surgery or other pathologies. If patients have adverse reactions such as thrombotic thrombocytopenic purpura (TTP), dizziness, gastric bleeding, bleeding gums, etc., the drug should be discontinued or reduced in dosage as appropriate under the supervision of a doctor. The use of drugs should be carried out under the guidance of a doctor, the occurrence of adverse drug reactions to seek medical attention in time to avoid the development of the disease.