High prolactin may be physiological or caused by drugs, hypothyroidism, pituitary adenoma, etc. Physiological and drug-induced can be self-cured, while hypothyroidism and pituitary adenoma-induced will not be self-cured. 1. Physiological: If the patient has poor mood, irregular life, physical weakness, etc., it may lead to fluctuation of prolactin and the phenomenon of high prolactin. Generally, it can be self-cured after proper adjustment of life habits. 2. Drugs: If you take birth control pills, domperidone tablets and other drugs may also lead to high prolactin, usually after stopping the drug can be self-cured. 3. Hypothyroidism: this disease will lead to a decrease in the level of thyroid hormone, thyrotropin level increases, which can promote the release of prolactin, resulting in high prolactin. The disease usually cannot be cured by itself and requires lifelong replacement therapy, the main drug is levothyroxine. 4. Pituitary adenoma: Pituitary adenoma may be related to the hypothalamus endocrine disorders, may also be related to drugs, in the examination will find high prolactin, can not be cured. Patients need comprehensive treatment, and can undergo surgery to remove the tumor, commonly used transnasal pterygoid sinus approach surgery, transfrontal approach surgery and so on. After surgery with radiotherapy, can also use bromocriptine and other drugs treatment. Therefore, patients with high prolactin can seek medical treatment for relevant examinations, clarify the cause of the disease under the guidance of the doctor, and treat the symptoms.