A white patch on the buttocks may be caused by vitiligo, post-inflammatory hypopigmented spots, and an unpigmented nevus. Can be given hormones, calcium-modulated neurophosphatase inhibitors, if necessary, through surgery for treatment. 1. Vitiligo: the cause of vitiligo has not been completely clear, if it occurs in the buttocks, resulting in local skin hypopigmentation and whitening. Can be used topically halometasone, mometasone furoate, etc., to prevent proliferation, restore part of the skin color. Topical tacrolimus and pimecrolimus can be used as maintenance therapy to restore part of the skin color. 2. Post-inflammatory hypopigmented spots: local pigment synthesis is abnormal after inflammation, resulting in local white patches. Some traumatic hypopigmented spots can recover on their own, and if necessary, the primary disease should be treated. 3. Nevus aphakia: nevus aphakia, also called depigmented nevus, is a rare, congenital and limited pigment loss spot. There is no effective medicine for the time being. If necessary, it can be covered by masking cream or autologous epidermal transplantation to help improve the patient’s appearance. The causes of white patches on the buttocks are more, it is recommended to pay strict attention to sun protection, timely to the hospital dermatology department for examination, clear diagnosis, follow the doctor’s instructions for medication, do not self-medication.